Phagocyte NADPH Oxidase, but Not Inducible Nitric Oxide Synthase, Is Essential for Early Control of Burkholderia cepacia and Chromobacterium violaceum Infection in Mice

Reactive oxygen and nitrogen intermediates have critical, partially overlapping roles in host defense against a variety of pathogens. Using mice deficient in generating phagocyte superoxide (p47(phox)(−/−)) and mice deficient in generating inducible nitric oxide synthase (iNOS(−/−)), we examined the...

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Bibliografiska uppgifter
Huvudupphovsmän: Segal, Brahm H., Ding, Li, Holland, Steven M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Host Response and Inflammation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC143145/
https://ncbi.nlm.nih.gov/pubmed/12496167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.205-210.2003
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