Phagocyte NADPH Oxidase, but Not Inducible Nitric Oxide Synthase, Is Essential for Early Control of Burkholderia cepacia and Chromobacterium violaceum Infection in Mice

Reactive oxygen and nitrogen intermediates have critical, partially overlapping roles in host defense against a variety of pathogens. Using mice deficient in generating phagocyte superoxide (p47(phox)(−/−)) and mice deficient in generating inducible nitric oxide synthase (iNOS(−/−)), we examined the...

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Pubblicato in:	Infect Immun
Autori principali:	Segal, Brahm H., Ding, Li, Holland, Steven M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Host Response and Inflammation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.205-210.2003
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