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Phagocyte NADPH Oxidase, but Not Inducible Nitric Oxide Synthase, Is Essential for Early Control of Burkholderia cepacia and Chromobacterium violaceum Infection in Mice
Reactive oxygen and nitrogen intermediates have critical, partially overlapping roles in host defense against a variety of pathogens. Using mice deficient in generating phagocyte superoxide (p47(phox)(−/−)) and mice deficient in generating inducible nitric oxide synthase (iNOS(−/−)), we examined the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC143145/ https://ncbi.nlm.nih.gov/pubmed/12496167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.205-210.2003 |
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