Protection from reoxygenation injury by inhibition of rac1.

We demonstrate that adenoviral-mediated gene transfer of a dominant negative rac1 gene product (N17rac1) inhibits the intracellular burst of reactive oxygen species (ROS) that occurs after reoxygenation of vascular smooth muscle cells. In contrast, expression of a dominant negative ras gene (N17ras)...

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Detalhes bibliográficos
Main Authors: Kim, K S, Takeda, K, Sethi, R, Pracyk, J B, Tanaka, K, Zhou, Y F, Yu, Z X, Ferrans, V J, Bruder, J T, Kovesdi, I, Irani, K, Goldschmidt-Clermont, P, Finkel, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508766/
https://ncbi.nlm.nih.gov/pubmed/9576744
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