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rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation.

The signal transduction pathway leading to the activation of the transcription factor NF-kappaB remains incompletely characterized. We demonstrate that in HeLa cells, transient expression of a constitutively active mutant of the small GTP-binding protein rac1 (V12rac1) leads to a significant increas...

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Detalhes bibliográficos
Main Authors: Sulciner, D J, Irani, K, Yu, Z X, Ferrans, V J, Goldschmidt-Clermont, P, Finkel, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231715/
https://ncbi.nlm.nih.gov/pubmed/8943367
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