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β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis

Trabecular bone formation is the last step in endochondral ossification. This remodeling process of cartilage into bone involves blood vessel invasion and removal of hypertrophic chondrocytes (HTCs) by chondroclasts and osteoclasts. Periosteal- and chondrocyte-derived osteoprogenitors utilize the le...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Houben, Astrid, Kostanova-Poliakova, Daniela, Weissenböck, Martina, Graf, Julian, Teufel, Stefan, von der Mark, Klaus, Hartmann, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087647/
https://ncbi.nlm.nih.gov/pubmed/27621061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137489
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