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β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis

Trabecular bone formation is the last step in endochondral ossification. This remodeling process of cartilage into bone involves blood vessel invasion and removal of hypertrophic chondrocytes (HTCs) by chondroclasts and osteoclasts. Periosteal- and chondrocyte-derived osteoprogenitors utilize the le...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Houben, Astrid, Kostanova-Poliakova, Daniela, Weissenböck, Martina, Graf, Julian, Teufel, Stefan, von der Mark, Klaus, Hartmann, Christine
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087647/
https://ncbi.nlm.nih.gov/pubmed/27621061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137489
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