cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner

cAMP-dependent protein kinase A (PKA) is a ubiquitously expressed serine/threonine kinase that regulates a variety of cellular functions. Here, we demonstrate that endothelial PKA activity is essential for vascular development, specifically regulating the transition from sprouting to stabilization o...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Nedvetsky, Pavel I., Zhao, Xiaocheng, Mathivet, Thomas, Aspalter, Irene M., Stanchi, Fabio, Metzger, Ross J., Mostov, Keith E., Gerhardt, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087612/
https://ncbi.nlm.nih.gov/pubmed/27702786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.134767
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