Optimizing Porcine Islet Isolation to Markedly Reduce Enzyme Consumption Without Sacrificing Islet Yield or Function

BACKGROUND: Human allogeneic islet transplantation for treatment of type 1 diabetes provides numerous clinical benefits, such as fewer episodes of hypoglycemic unawareness and tighter control of blood glucose levels. Availability of human pancreas for clinical and research use, however, is severely...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Holdcraft, Robert W., Green, Michael L., Breite, Andrew G., Circle, Lisa, Meyer, Eric D., Adkins, Hollie, Harbeck, Steven G., Smith, Barry H., Gazda, Lawrence S.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Pancreas and Islet Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087567/
https://ncbi.nlm.nih.gov/pubmed/27830180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000599
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