Identifying Effective Enzyme Activity Targets for Recombinant Class I and Class II Collagenase for Successful Human Islet Isolation

Isolation following a good manufacturing practice-compliant, human islet product requires development of a robust islet isolation procedure where effective limits of key reagents are known. The enzymes used for islet isolation are critical but little is known about the doses of class I and class II...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Balamurugan, Appakalai N., Green, Michael L., Breite, Andrew G., Loganathan, Gopalakrishnan, Wilhelm, Joshua J., Tweed, Benjamin, Vargova, Lenka, Lockridge, Amber, Kuriti, Manikya, Hughes, Michael G., Williams, Stuart K., Hering, Bernhard J., Dwulet, Francis E., McCarthy, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Pancreas and Islet Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946501/
https://ncbi.nlm.nih.gov/pubmed/27500247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000563
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