MALT1 protease activation triggers acute disruption of endothelial barrier integrity via CYLD cleavage

Microvascular endothelial cells maintain a tight barrier to prevent passage of plasma and circulating immune cells into the extravascular tissue compartment. Yet endothelial cells respond rapidly to vasoactive substances, including thrombin, allowing transient paracellular permeability. This respons...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Klei, Linda R., Hu, Dong, Panek, Robert, Alfano, Danielle N., Bridwell, Rachel E., Bailey, Kelly M., Oravecz-Wilson, Katherine I., Concel, Vincent J., Hess, Emily M., Van Beek, Matthew, Delekta, Phillip C., Gu, Shufang, Watkins, Simon C., Ting, Adrian T., Gough, Peter J., Foley, Kevin P., Bertin, John, McAllister-Lucas, Linda M., Lucas, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087334/
https://ncbi.nlm.nih.gov/pubmed/27681433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.080
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