CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Complex interactions between the host and the gut microbiota govern intestinal homeostasis but remain poorly understood. Here we reveal a relationship between gut microbiota and caspase recruitment domain family member 9 (CARD9), a susceptibility gene for inflammatory bowel disease (IBD) that functi...

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Detaylı Bibliyografya
Yayımlandı:Nat Med
Asıl Yazarlar: Lamas, Bruno, Richard, Mathias L, Leducq, Valentin, Pham, Hang-Phuong, Michel, Marie-Laure, Da Costa, Gregory, Bridonneau, Chantal, Jegou, Sarah, Hoffmann, Thomas W, Natividad, Jane M, Brot, Loic, Taleb, Soraya, Couturier-Maillard, Aurélie, Nion-Larmurier, Isabelle, Merabtene, Fatiha, Seksik, Philippe, Bourrier, Anne, Cosnes, Jacques, Ryffel, Bernhard, Beaugerie, Laurent, Launay, Jean-Marie, Langella, Philippe, Xavier, Ramnik J, Sokol, Harry
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087285/
https://ncbi.nlm.nih.gov/pubmed/27158904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4102
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