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CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Complex interactions between the host and the gut microbiota govern intestinal homeostasis but remain poorly understood. Here we reveal a relationship between gut microbiota and caspase recruitment domain family member 9 (CARD9), a susceptibility gene for inflammatory bowel disease (IBD) that functi...

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書誌詳細
出版年:Nat Med
主要な著者: Lamas, Bruno, Richard, Mathias L, Leducq, Valentin, Pham, Hang-Phuong, Michel, Marie-Laure, Da Costa, Gregory, Bridonneau, Chantal, Jegou, Sarah, Hoffmann, Thomas W, Natividad, Jane M, Brot, Loic, Taleb, Soraya, Couturier-Maillard, Aurélie, Nion-Larmurier, Isabelle, Merabtene, Fatiha, Seksik, Philippe, Bourrier, Anne, Cosnes, Jacques, Ryffel, Bernhard, Beaugerie, Laurent, Launay, Jean-Marie, Langella, Philippe, Xavier, Ramnik J, Sokol, Harry
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087285/
https://ncbi.nlm.nih.gov/pubmed/27158904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4102
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