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L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.

The effective action of endothelium-derived nitric oxide (EDNO) is impaired in patients with atherosclerosis. This impairment has been attributed in part to increased vascular oxidative stress. EDNO action is improved by administration of ascorbic acid, a water-soluble antioxidant. Ascorbic acid is...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Vita, J A, Frei, B, Holbrook, M, Gokce, N, Leaf, C, Keaney, J F
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9502783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1155
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