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Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence

Since the emergence of human H3N2 influenza A viruses in the pandemic of 1968, these viruses have become established as strains of moderate severity. A decline in virulence has been accompanied by glycan accumulation on the hemagglutinin globular head, and hemagglutinin receptor binding has changed...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Alymova, Irina V., York, Ian A., Air, Gillian M., Cipollo, John F., Gulati, Shelly, Baranovich, Tatiana, Kumar, Amrita, Zeng, Hui, Gansebom, Shane, McCullers, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086918/
https://ncbi.nlm.nih.gov/pubmed/27796371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36216
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