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Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats.

Troglitazone (CS-045) is one of the thiazolidinediones that activate the peroxisome proliferator-activated receptor gamma (PPARgamma), which is expressed primarily in adipose tissues. To elucidate the mechanism by which troglitazone relieves insulin resistance in vivo, we studied its effects on the...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Okuno, A, Tamemoto, H, Tobe, K, Ueki, K, Mori, Y, Iwamoto, K, Umesono, K, Akanuma, Y, Fujiwara, T, Horikoshi, H, Yazaki, Y, Kadowaki, T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9502777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1235
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