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A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma

Despite advances in clinical management, 5-year survival rate in patients with late-stage head and neck squamous cell carcinoma (HNSCC) has not improved significantly over the past decade. Targeted therapies have emerged as one of the most promising approaches to treat several malignancies. Though t...

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Publicado no:Sci Rep
Main Authors: Radhakrishnan, Aneesha, Nanjappa, Vishalakshi, Raja, Remya, Sathe, Gajanan, Puttamallesh, Vinuth N., Jain, Ankit P., Pinto, Sneha M., Balaji, Sai A., Chavan, Sandip, Sahasrabuddhe, Nandini A., Mathur, Premendu P., Kumar, Mahesh M., Prasad, T. S. Keshava, Santosh, Vani, Sukumar, Geethanjali, Califano, Joseph A., Rangarajan, Annapoorni, Sidransky, David, Pandey, Akhilesh, Gowda, Harsha, Chatterjee, Aditi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086852/
https://ncbi.nlm.nih.gov/pubmed/27796319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36132
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