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Excess Testosterone Exposure Alters Hypothalamic-Pituitary-Testicular Axis Dynamics and Gene Expression in Sheep Fetuses

Prenatal exposure to excess androgen may result in impaired adult fertility in a variety of mammalian species. However, little is known about what feedback mechanisms regulate gonadotropin secretion during early gestation and how they respond to excess T exposure. The objective of this study was to...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Roselli, Charles E., Amodei, Rebecka, Gribbin, Kyle P., Corder, Keely, Stormshak, Fred, Estill, Charles T.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086533/
https://ncbi.nlm.nih.gov/pubmed/27673555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1411
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