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Characterisation of Drosophila CMP-sialic acid synthetase activity reveals unusual enzymatic properties

CMP-sialic acid synthetase (CSAS) is a key enzyme of the sialylation pathway. CSAS produces the activated sugar donor, CMP-sialic acid, which serves as a substrate for sialyltransferases to modify glycan termini with sialic acid. Unlike other animal CMP-Sia synthetases that normally localize in the...

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Bibliografische gegevens
Gepubliceerd in:Biochem J
Hoofdauteurs: Mertsalov, Ilya B., Novikov, Boris N., Scott, Hilary, Dangott, Lawrence, Panin, Vladislav M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086458/
https://ncbi.nlm.nih.gov/pubmed/27114558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160347
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