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Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.

A consistent phenotype observed in both human patients and several different mouse models of autosomal recessive polycystic kidney disease (ARPKD) is an increased activity of the epidermal growth factor receptor (EGFR) in the affected kidneys. To determine whether this increased activity of the EGFR...

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Published in:J Clin Invest
Main Authors: Richards, W G, Sweeney, W E, Yoder, B K, Wilkinson, J E, Woychik, R P, Avner, E D
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1998
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9486961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2071
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