Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.

A consistent phenotype observed in both human patients and several different mouse models of autosomal recessive polycystic kidney disease (ARPKD) is an increased activity of the epidermal growth factor receptor (EGFR) in the affected kidneys. To determine whether this increased activity of the EGFR...

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Publié dans:	J Clin Invest
Auteurs principaux:	Richards, W G, Sweeney, W E, Yoder, B K, Wilkinson, J E, Woychik, R P, Avner, E D
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1998
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9486961/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2071
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