Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure.

The p21 protein is found in the nucleus of most cells at low levels and is induced to elevated levels after DNA damage, causing cell-cycle arrest. We have reported that p21 mRNA is rapidly induced to high levels in murine kidney after acute renal failure. The function(s) in the kidney of p21 inducti...

Celý popis

Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Megyesi, J, Safirstein, R L, Price, P M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1998
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9466972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1497
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!