Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure.

The p21 protein is found in the nucleus of most cells at low levels and is induced to elevated levels after DNA damage, causing cell-cycle arrest. We have reported that p21 mRNA is rapidly induced to high levels in murine kidney after acute renal failure. The function(s) in the kidney of p21 inducti...

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-д хэвлэсэн:	J Clin Invest
Үндсэн зохиолчид:	Megyesi, J, Safirstein, R L, Price, P M
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Clinical Investigation 1998
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9466972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1497
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