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Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide

Ceramide is a common precursor of sphingomyelin (SM) and glycosphingolipids (GSLs) in mammalian cells. Ceramide synthase 2 (CERS2), one of the six ceramide synthase isoforms, is responsible for the synthesis of very long chain fatty acid (C20–26 fatty acids) (VLC)-containing ceramides (VLC-Cer). It...

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Pubblicato in:Int J Mol Sci
Autori principali: Yamaji, Toshiyuki, Horie, Aya, Tachida, Yuriko, Sakuma, Chisato, Suzuki, Yusuke, Kushi, Yasunori, Hanada, Kentaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085785/
https://ncbi.nlm.nih.gov/pubmed/27775668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101761
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