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Cinnamide Derivatives as Mammalian Arginase Inhibitors: Synthesis, Biological Evaluation and Molecular Docking

Arginases are enzymes that are involved in many human diseases and have been targeted for new treatments. Here a series of cinnamides was designed, synthesized and evaluated in vitro and in silico for their inhibitory activity against mammalian arginase. Using a microassay on purified liver bovine a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Pham, Thanh-Nhat, Bordage, Simon, Pudlo, Marc, Demougeot, Céline, Thai, Khac-Minh, Girard-Thernier, Corine
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085689/
https://ncbi.nlm.nih.gov/pubmed/27690022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101656
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