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Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1

The mammalian target of rapamycin (mTOR) is the central regulator of mammalian cell growth, and is essential for the formation of two structurally and functionally distinct complexes: mTORC1 and mTORC2. mTORC1 can sense multiple cues such as nutrients, energy status, growth factors and hormones to c...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Zheng, Liufeng, Zhang, Wei, Zhou, Yuanfei, Li, Fengna, Wei, Hongkui, Peng, Jian
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085669/
https://ncbi.nlm.nih.gov/pubmed/27690010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101636
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