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Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity
BM-derived DC (BMDC) are powerful antigen-presenting cells. When loaded with immune complexes (IC), consisting of tumor antigens bound to antitumor antibody, BMDC induce powerful antitumor immunity in mice. However, attempts to employ this strategy clinically with either tumor-associated DC (TADC) o...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | JCI Insight |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085602/ https://ncbi.nlm.nih.gov/pubmed/27812544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89020 |
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