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Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity

BM-derived DC (BMDC) are powerful antigen-presenting cells. When loaded with immune complexes (IC), consisting of tumor antigens bound to antitumor antibody, BMDC induce powerful antitumor immunity in mice. However, attempts to employ this strategy clinically with either tumor-associated DC (TADC) o...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:JCI Insight
Κύριοι συγγραφείς: Carmi, Yaron, Prestwood, Tyler R., Spitzer, Matthew H., Linde, Ian L., Chabon, Jonathan, Reticker-Flynn, Nathan E., Bhattacharya, Nupur, Zhang, Hong, Zhang, Xiangyue, Basto, Pamela A., Burt, Bryan M., Alonso, Michael N., Engleman, Edgar G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085602/
https://ncbi.nlm.nih.gov/pubmed/27812544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89020
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