Enhancement of rabbit jugular vein thrombolysis by neutralization of factor XI. In vivo evidence for a role of factor XI as an anti-fibrinolytic factor.

Recent in vitro studies have shown that fibrinolytic activity may be attenuated by a thrombin-activatable fibrinolysis inhibitor (TAFI), which is activated by thrombin, generated via the intrinsic pathway of coagulation in a factor XI-dependent way. Thus factor XI may play a role in the regulation o...

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Hauptverfasser: Minnema, M C, Friederich, P W, Levi, M, von dem Borne, P A, Mosnier, L O, Meijers, J C, Biemond, B J, Hack, C E, Bouma, B N, ten Cate, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508534/
https://ncbi.nlm.nih.gov/pubmed/9421460
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