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De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds

A major goal in metalloprotein design is to build protein scaffolds from scratch that allow precise control over metal coordination. A particular challenge in this regard is the construction of allosteric systems in which metal coordination equilibria are coupled to other chemical events that take p...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Churchfield, Lewis A., Medina-Morales, Annette, Brodin, Jeffrey D., Perez, Alfredo, Tezcan, F. Akif
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085265/
https://ncbi.nlm.nih.gov/pubmed/27649076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b08458
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