Characterization of the novel indolylmaleimides' PDA-66 and PDA-377 effect on canine lymphoma cells

Protein kinase inhibitors are widely used in chemotherapeutic cancer regimens. Maleimide derivatives such as SB-216763 act as GSK-3 inhibitor targeting cell proliferation, cell death and cell cycle progression. Herein, the two arylindolylmaleimide derivatives PDA-66 and PDA-377 were evaluated as pot...

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Udgivet i:Oncotarget
Main Authors: Liu, Wen, Beck, Julia, Schmidt, Laura C., Roolf, Catrin, Pews-Davtyan, Anahit, Rütgen, Barbara C., Hammer, Sabine, Willenbrock, Saskia, Sekora, Anett, Rolfs, Arndt, Beller, Matthias, Brenig, Bertram, Nolte, Ingo, Junghanss, Christian, Schütz, Ekkehard, Escobar, Hugo Murua
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085236/
https://ncbi.nlm.nih.gov/pubmed/27177088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9297
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