Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

The pathogenesis and etiology of Hodgkin's disease, a common human malignant lymphoma, is still unresolved. As a unique characteristic, we have identified constitutive activation of the transcription factor nuclear factor (NF)-kappaB p50-RelA in Hodgkin/Reed-Sternberg (H/RS) cells, which discri...

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Main Authors: Bargou, R C, Emmerich, F, Krappmann, D, Bommert, K, Mapara, M Y, Arnold, W, Royer, H D, Grinstein, E, Greiner, A, Scheidereit, C, Dörken, B
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC508507/
https://ncbi.nlm.nih.gov/pubmed/9399941
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