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Regulation of nuclear translocation of nuclear factor-kappaB relA: evidence for complex dynamics at the single-cell level.

We have analysed activation of nuclear factor-kappaB (NF-kappaB) in response to interleukin-1 (IL-1) in human fibroblasts by tracking intracellular distribution and levels of endogenous relA, NF-kappaB1 and inhibitor of kappaB (I-kappaB) alpha using semi-quantitative confocal microscopy. Nuclear tra...

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Detalhes bibliográficos
Main Authors: Schooley, Kenneth, Zhu, Ping, Dower, Steven K, Qwarnström, Eva E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223076/
https://ncbi.nlm.nih.gov/pubmed/12350227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020253
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