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Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

Perineural invasion (PNI) is thought to be one of the factors responsible for the high rate of tumor recurrence after surgery and the pain generation associated with pancreatic cancer. Signaling via the nerve growth factor (NGF) pathway between pancreatic cancer cells and the surrounding nerves has...

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Publicado en:PLoS One
Autores principales: Bapat, Aditi A., Munoz, Ruben M., Von Hoff, Daniel D., Han, Haiyong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085053/
https://ncbi.nlm.nih.gov/pubmed/27792755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165586
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