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Synergistic effect between erlotinib and MEK inhibitors in KRAS wildtype human pancreatic cancer cells

PURPOSE: The combination of gemcitabine plus erlotinib has shown a small but statistically significant survival advantage when compared to gemcitabine alone in patients with advanced pancreatic cancer. However, the overall survival rate with the erlotinib and gemcitabine combination is still low. In...

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Bibliografiset tiedot
Päätekijät: Diep, Caroline H., Munoz, Ruben M., Choudhary, Ashish, Von Hoff, Daniel D., Han, Haiyong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265169/
https://ncbi.nlm.nih.gov/pubmed/21385921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2214
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