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Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

Perineural invasion (PNI) is thought to be one of the factors responsible for the high rate of tumor recurrence after surgery and the pain generation associated with pancreatic cancer. Signaling via the nerve growth factor (NGF) pathway between pancreatic cancer cells and the surrounding nerves has...

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Vydáno v:PLoS One
Hlavní autoři: Bapat, Aditi A., Munoz, Ruben M., Von Hoff, Daniel D., Han, Haiyong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085053/
https://ncbi.nlm.nih.gov/pubmed/27792755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165586
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