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Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.

Vascular proliferative disorders are characterized by the proliferation of vascular smooth muscle cells (SMCs) and excessive extracellular matrix synthesis. We found that bone morphogenetic protein-2 (BMP-2) inhibited serum-stimulated increases in DNA synthesis and cell number of cultured rat arteri...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Nakaoka, T, Gonda, K, Ogita, T, Otawara-Hamamoto, Y, Okabe, F, Kira, Y, Harii, K, Miyazono, K, Takuwa, Y, Fujita, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508488/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9389748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119830
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