Adventitial Fibroblasts Release Interleukin 6 After Vascular Injury and Induce Smooth Muscle Cell Proliferation and Neointima Formation

Background Vascular restenosis resulting from neointima formation significantly limits the efficacy of percutaneous interventional therapies compared with bypass surgery. The adventitial layer is involved in neointima formation, but the detailed pathophysiological interplay of the different cell typ...

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Autori principali:	Jochen Dutzmann, Jan‐Marcus Daniel, Laura Korte, Frederik J. Kloss, Kai Knöpp, Katrin Kalies, Kevin J. Croce, Thomas J. Herbst, Barbara Huibregtse, Felix J. Vogt, Stefan Offermanns, Johann Bauersachs, Daniel G. Sedding
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2025-07-01
Serie:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Soggetti:	adventitial fibroblasts interleukin 6 neointima formation paracrine signaling smooth muscle cells vascular restenosis
Accesso online:	https://www.ahajournals.org/doi/10.1161/JAHA.124.040143
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