Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein.

Mucin 1 (MUC1) is a large complex glycoprotein that is highly expressed in breast cancer, and as such could be a target for immunotherapy. In mice, human MUC1 is highly immunogenic, particularly when conjugated to mannan, where a high frequency of CD8(+) MHC-restricted cytotoxic T lymphocytes is ind...

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Detalhes bibliográficos
Main Authors: Karanikas, V, Hwang, L A, Pearson, J, Ong, C S, Apostolopoulos, V, Vaughan, H, Xing, P X, Jamieson, G, Pietersz, G, Tait, B, Broadbent, R, Thynne, G, McKenzie, I F
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508483/
https://ncbi.nlm.nih.gov/pubmed/9389743
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