Production of anti-breast cancer monoclonal antibodies using a glutathione-S-transferase-MUC1 bacterial fusion protein.

Two murine Mabs VA1(IgG1) and VA2(IgG1) were produced against a bacterial fusion protein comprising glutathione S-transferase and five tandem repeats of the MUC1 protein. Using the immunoperoxidase staining technique, VA1 detected 46/53 and VA2 detected 48/53 breast cancers and both also reacted wit...

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Detalles Bibliográficos
Main Authors: Apostolopoulos, V., Xing, P. X., Trapani, J. A., McKenzie, I. F.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968353/
https://ncbi.nlm.nih.gov/pubmed/7682431
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