Loss of YAP1 defines neuroendocrine differentiation of lung tumors

YAP1, the main Hippo pathway effector, is a potent oncogene and is overexpressed in non‐small‐cell lung cancer (NSCLC); however, the YAP1 expression pattern in small‐cell lung cancer (SCLC) has not yet been elucidated in detail. We report that the loss of YAP1 is a special feature of high‐grade neur...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ito, Takeshi, Matsubara, Daisuke, Tanaka, Ichidai, Makiya, Kanae, Tanei, Zen‐ichi, Kumagai, Yuki, Shiu, Shu‐Jen, Nakaoka, Hiroki J., Ishikawa, Shumpei, Isagawa, Takayuki, Morikawa, Teppei, Shinozaki‐Ushiku, Aya, Goto, Yasushi, Nakano, Tomoyuki, Tsuchiya, Takehiro, Tsubochi, Hiroyoshi, Komura, Daisuke, Aburatani, Hiroyuki, Dobashi, Yoh, Nakajima, Jun, Endo, Shunsuke, Fukayama, Masashi, Sekido, Yoshitaka, Niki, Toshiro, Murakami, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084673/
https://ncbi.nlm.nih.gov/pubmed/27418196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13013
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