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Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype.

The diversity among cyclic nucleotide phosphodiesterases provides multiple mechanisms for regulation of cAMP and cGMP in the cardiovascular system. Here we report that a calmodulin-stimulated phosphodiesterase (PDE1C) is highly expressed in proliferating human arterial smooth muscle cells (SMCs) in...

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Autori principali: Rybalkin, S D, Bornfeldt, K E, Sonnenburg, W K, Rybalkina, I G, Kwak, K S, Hanson, K, Krebs, E G, Beavo, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508463/
https://ncbi.nlm.nih.gov/pubmed/9366577
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