Lupus-specific antibodies reveal an altered pattern of somatic mutation.

The F4 idiotype is a heavy chain determinant expressed almost exclusively on IgG immunoglobulins and is highly associated with specificity for double-stranded DNA. Since high-titered F4 expression is present predominantly in sera of patients with systemic lupus erythematosus (SLE), we thought F4+ Ig...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Manheimer-Lory, A J, Zandman-Goddard, G, Davidson, A, Aranow, C, Diamond, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9366568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119796
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