Lupus-specific antibodies reveal an altered pattern of somatic mutation.
The F4 idiotype is a heavy chain determinant expressed almost exclusively on IgG immunoglobulins and is highly associated with specificity for double-stranded DNA. Since high-titered F4 expression is present predominantly in sera of patients with systemic lupus erythematosus (SLE), we thought F4+ Ig...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9366568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119796 |
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