Specific depletion of the B-cell population induced by aberrant expression of human interferon regulatory factor 1 gene in transgenic mice.

Interferons (IFNs) are well known both as antiviral proteins and as potent regulators of cell growth and differentiation. In fact, IFNs inhibit growth of various normal and transformed cell types. Previously, a nuclear factor, IRF-1 (interferon regulatory factor 1), which binds to type I IFN and som...

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Main Authors: Yamada, G, Ogawa, M, Akagi, K, Miyamoto, H, Nakano, N, Itoh, S, Miyazaki, J, Nishikawa, S, Yamamura, K, Taniguchi, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50845/
https://ncbi.nlm.nih.gov/pubmed/1988951
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