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Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin.

During B cell differentiation, at least three stages can be defined in terms of their growth signal requirement by using two different growth signals, which are recombinant interleukin 7 (IL-7) and a stromal cell clone PA6 which does not produce IL-7; first a PA6 dependent stage, second a PA6 + IL-7...

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Autores principales: Era, T, Ogawa, M, Nishikawa, S, Okamoto, M, Honjo, T, Akagi, K, Miyazaki, J, Yamamura, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC452651/
https://ncbi.nlm.nih.gov/pubmed/1899373
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