Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.

This study was performed to test the hypothesis that cytotoxic T lymphocyte (CTL) selection of hepatitis C virus (HCV) escape variants plays a role in HCV persistence. The peripheral blood CTL responsiveness of patients with well-established chronic hepatitis C to a panel of 10 prototype HCV peptide...

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Bibliographic Details
Main Authors: Chang, K M, Rehermann, B, McHutchison, J G, Pasquinelli, C, Southwood, S, Sette, A, Chisari, F V
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508436/
https://ncbi.nlm.nih.gov/pubmed/9410918
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