Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.

This study was performed to test the hypothesis that cytotoxic T lymphocyte (CTL) selection of hepatitis C virus (HCV) escape variants plays a role in HCV persistence. The peripheral blood CTL responsiveness of patients with well-established chronic hepatitis C to a panel of 10 prototype HCV peptide...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Chang, K M, Rehermann, B, McHutchison, J G, Pasquinelli, C, Southwood, S, Sette, A, Chisari, F V
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9410918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119778
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