Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy

BACKGROUND: MEK1 (MAP2K1) and MEK2 (MAP2K2) are closely related dual-specificity protein kinases which function by phosphorylating both serine/threonine and tyrosine residues of their substrates ERK1 and ERK2, controlling fundamental cellular processes that include cell growth and proliferation. To...

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Vydáno v:BMC Cancer
Hlavní autoři: Gomez-Millan, J., Pajares, B., Perez-Villa, L., Carnero, A., Alvarez, M., De Luque, V., Rivas, F., Trigo, J. M., Toledo, M. D., Alba, E., Medina, J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084350/
https://ncbi.nlm.nih.gov/pubmed/27793200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2869-x
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