Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

Alzheimer's disease is a neurodegenerative disorder characterized by the extracellular deposition in the brain of aggregated beta-amyloid peptide, presumed to play a pathogenic role, and by preferential loss of neurons that express the 75-kD neurotrophin receptor (p75NTR). Using rat cortical ne...

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Main Authors: Yaar, M, Zhai, S, Pilch, P F, Doyle, S M, Eisenhauer, P B, Fine, R E, Gilchrest, B A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1997
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC508430/
https://ncbi.nlm.nih.gov/pubmed/9410912
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