Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products.

Animal studies indicate that the use of replication-deficient adenovirus for human gene therapy is limited by host antivector immune responses that result in transient recombinant protein expression and blocking of gene transfer when rechallenged. Therefore, we have examined immune responses to an a...

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Detalhes bibliográficos
Main Authors: Gahéry-Ségard, H, Molinier-Frenkel, V, Le Boulaire, C, Saulnier, P, Opolon, P, Lengagne, R, Gautier, E, Le Cesne, A, Zitvogel, L, Venet, A, Schatz, C, Courtney, M, Le Chevalier, T, Tursz, T, Guillet, J G, Farace, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508417/
https://ncbi.nlm.nih.gov/pubmed/9410899
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