Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products.

Animal studies indicate that the use of replication-deficient adenovirus for human gene therapy is limited by host antivector immune responses that result in transient recombinant protein expression and blocking of gene transfer when rechallenged. Therefore, we have examined immune responses to an a...

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Main Authors: Gahéry-Ségard, H, Molinier-Frenkel, V, Le Boulaire, C, Saulnier, P, Opolon, P, Lengagne, R, Gautier, E, Le Cesne, A, Zitvogel, L, Venet, A, Schatz, C, Courtney, M, Le Chevalier, T, Tursz, T, Guillet, J G, Farace, F
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508417/
https://ncbi.nlm.nih.gov/pubmed/9410899
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